Sam Wood - Stamboul Quest (1934)

The real-life career of the notorious female spy known as “Fraulein Doktor” inspired several films of the 1930s. Stamboul Quest stars Myrna Loy as a seductive espionage agent, working on behalf of the Kaiser in 1915 Istanbul. American medical student George Brent crosses Loy’s path, and the two fall in love. Divided between romance and duty, Loy opts for the latter, and apparently causes Brent’s death. She goes mad with grief, and is packed away to a mental institution, where her fevered reminiscences provide the lengthy flashback sequences in this film. ~ Hal Erickson, All Movie Guide